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L-Glutamine supplementation (typically 5-10 grams daily) has been shown to support immune cell activity, potentially reducing illness frequency in athletes

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Administration of spironolactone, a selective MR antagonist, counteracted stress-induced mGlu2 suppression and the related development of depressive-like behavior, implicating rapid action of glucocorticoids via a receptor that is known to modulate glutamate release [20]

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