melanotan boners II (“Tan Jabs”): Why They're Not Worth The Risk A warning about an unregulated

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4,173 Views 149 Download 1 Crossref Abstract The scope of gene fusions in melanocytic neoplasms is broader than previously recognized, extending well beyond the Spitz-lineage neoplasms where kinase fusions involving ALK , ROS1 , NTRK1/2/3 , RET , MET , BRAF , and MAP3K8 define biologically and morphologically distinct tumors

Cavo M, Rajkumar SV, Palumbo A, Moreau P, Orlowski R, Blad J, Sezer O, Ludwig H, Dimopoulos MA, Attal M, Sonneveld P, Boccadoro M, Anderson KC, Richardson PG, Bensinger W, Johnsen HE, Kroeger N, Gahrton G, Bergsagel PL, Vesole DH, Einsele H, Jagannath S, Niesvizky R, Durie BG, San Miguel J, Lonial S, Working Group IM

Histologically, the tumor showed an epithelioid to spindle-shaped morphology with heavy melanotic pigmentation and moderate cellularity, arranged in short fascicles (Figure 2A)

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