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Enhanced Metabolic Health: Improved insulin sensitivity, reduced fasting glucose, and decreased HbA1c

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doi: 10.3389/fendo.2024.1431292 Received 11 May 2024 Accepted 08 July 2024 Published 24 July 2024 Volume 15 - 2024 Edited by Hisamitsu Ishihara, Nihon University, Japan Reviewed by Alessandro Pocai, Janssen Research and Development, United States Hiroshi Nomoto, Hokkaido University Hospital, Japan Updates Copyright 2024 Liu

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Results: Oral semaglutide reduced HbA1c levels compared to placebo Oral semaglutide patients experienced significant weight loss compared to those on placebo The primary outcome (composite of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke) occurred in 3.8% of patients in the oral semaglutide group and 4.8% in the placebo group, which showed that cardiovascular safety of oral semaglutide was non-inferior to placebo