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Description
EXS 100:397460
Abstract Pulmonary fibrosis is a fatal interstitial disease characterized by diffuse alveolitis, abnormal fibroblast proliferation, and extracellular matrix (ECM) accumulation, resulting in structural lung destruction and impaired lung function
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Based on the color evolution between colorless 3,3,5,5-tetramethylbenzidine (TMB) and blue oxTMB enable by oxidase-like pFeSAN and reductive GSH, pFeSAN is developed as a highly selective and sensitive probe for the rapid GSH detection with a low limit of detection (LOD) of 2.4 nM and a wide window (50 nM1 mM)
Intracellular ROS are primarily produced by mitochondrial metabolism
10.1016/S0021-9258(18)36026-5
