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Description
Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability
JAMA 313:2456
M.BabotaM.et al (2020)
Dihydrolipoic acid lowers the redox activity of transition metal ions but does not remove them from the active site of enzymes
One enzyme, glutathione peroxidase (GPx), works with glutathione to prevent membranes from becoming oxidized
This toxicity is characterized by specific microbial alterations and disrupted bile acid metabolism
