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2936 Evidence generated from experimental and observational clinical studies conducted over the last 30 years suggests that treatment with methotrexate is also associated with beneficial effects on surrogate markers of atherosclerosis and cardiovascular clinical endpoints, for example, myocardial infarction and stroke
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In particular, we will emphasize that the skin is a complex ecosystem in which regulation of the interactions between host cells and resident microbes determines the shift from homeostatic balance to aging or disease
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doi: 10.1002/(SICI)1097-0045(19990801)40:3 3.0.CO;2-3
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