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Furthermore, we postulate that the gut may serve as a reservoir for estrogenic metabolites capable of acting locally and perhaps distantly in systemic homeostasis and the development of disease

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Testosterone deficiency promotes hypercholesteremia and attenuates cholesterol liver uptake via AR/PCSK9/LDLR pathways

Recently, it was found that the accumulation of A in the vascular wall is linked to a range of aging-related vascular pathologies, indicating a potential role of A in the pathogenesis of aging-assocd