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Rather, it is a benchmark rate that is based on the general trend toward increasing rates of sustained virologic response in recent years and the general appeal of using a fixed, clinically relevant threshold as a measure of treatment benefit.16 We determined that the enrollment of 500 patients in the sofosbuvir-velpatasvir group would provide a power of 90% to detect an improvement of at least 5 percentage points in the rate of sustained virologic response over the performance goal of 85%, on the basis of the two-sided exact one-sample binomial test at the 0.05 significance level

elegans intestinal LROs contribute to basal heat stress tolerance as well as mediate the beneficial effects of hormetic BA preconditioning to mount an adaptive organismal response to heat and oxidative stress

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At the request of the board of trustees of Green-Wood Cemetery, his remains were brought there and interred in 1856

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Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, et al