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Another marker of L-Glu toxicity was DNA fragmentation, and this increased after 80 mM L-Glu administration for 24 h to SH-SY5Y cells [61]

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found that the disulfiram-Cu 2+ complex induced the production of ROS, which in turn activated downstream apoptosis-related JNK and p38MAPK pathways, thereby inducing breast cancer cell apoptosis [28]

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