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[PubMed] [Google Scholar] 12.Kendler B.S

TMAO stimulated gluconeogenesis and caused insulin resistance, which promoted the progression of diabetes (136)

It stimulates macrophages to release free cholesterol (55)

Moreover, quercetin suppressed hydrogen peroxide generation (originating from mitochondria) along with the elevation of mitochondrial peroxisome proliferator-activated receptor- coactivator 1 (PGC-1) mRNA expression (master regulator of mitochondrial biogenesis in the skeletal muscles) and NADH dehydrogenase-4 expression in the e gastrocnemius muscle in mice with SNX surgery

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