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These data were confirmed by a lower TEER in Ussing chambers (81, 82) and a decreased number of tight-junction strands shown by freeze-fracture electron microscopy (83)

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Funding This study was supported by grants from the Far-Eastern Memorial Hospital National Yang Ming Chiao Tung University Joint Research Program (109DN17)

Glutathione is a compound of the three amino acids glycine, cysteine and glutamic acid and occurs naturally in the body's cells

N -acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial