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It increases Hbs capacity to decompose H 2 O 2 , enabling up to 20% activity even at concentrations where native Hb alone exhibits negligible pseudoperoxidase function, highlighting KDS12025s potential to activate Hbs enzymatic role pharmacologically

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Furthermore, a clinical proof-of-concept study for intranasal insulin including 16 subjects with clinically diagnosed PD or multiple system atrophy [205] confirmed the safety and showed improvement of motor and cognitive symptoms

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Age-associated graying: steps toward slowing or stopping it Right now, research on reversing age-associated grey hair seems to focus primarily on (1) decreasing free radical activity in the hair bulb, and (2) increasing antioxidant activity at the hair bulb

Acknowledgements The authors work is supported by the NIH National Institute of Neurological Disorders and Stroke (grant number R21 NS114764-01A1)