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This leakage further activates microglia towards the M1 phenotype, promoting release of neurotoxic agents, including TNF- and IL-6 (50)

Furthermore, a study conducted by Pickert et

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Furthermore, studies examining the sensitivity of various bacterial species to oxidative killing by neutrophils suggest that these organisms are not uniformly sensitive to the oxidative burst of these cells

These molecules are exposed to series of reactions such as condensation, ring formation, and hydrolysis