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Mol Oncol

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Loss of primary pyruvate dehydrogenase complex enzymatic function may occur from loss of mRNA expression, subunit instability, or loss or reduction of functional activity of various primary pyruvate dehydrogenase complex-associated gene products (Table 2), which could, in part, be due to partial or complete deletion of the specific gene

2016;12(9):e1006251

Ensures all doses are administered within 14 days of reconstitution when peptide stability is highest

Brain 138 , 845861 (2015)