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Some agents have been shown to have direct cell cycle effects as a proposed mechanism of radioprotection
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A truly useful pLGG model would ideally recapitulate the molecular pathogenesis of human pLGGs along with the dependency of these tumors on the microenvironment milieu and the inevitable activation of the MAPK pathway
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Once the complex is assembled, the phagophore expands and envelopes preselected cargo
GH releasing hormone (GHRH) has been shown to potentiate the ACTH and cortisol response to insulin-induced hypoglycemia, but not to potentiate the ACTH and cortisol response after administration of CRH/AVP (114)
