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It can also increase your cells' all-important sensitivity to insulin [36] and has anti-catabolic [37,38] and cardioprotective [39] effects

doi: 10.3390/molecules20021904 512 XinYJYuanBYuBWangYQWuJJZhouWHet al

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This alteration leads to an increase in primary and conjugated bile acids (e.g., cholic acid, taurocholate, and glycocholic acid, chenodeoxycholic acid) and a decrease in secondary bile acids

Impaired mitochondrial fusion and enhanced mitochondrial fission have been reported in mice with Mfn2 gene knockout, which was accompanied by metabolic disorders such as glucose intolerance, enhanced hepatic gluconeogenesis, and leptin resistance (66, 103)