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Hormone signaling Local estrogen production may play a pathophysiological role in endometriosis by enhancing the inflammatory status of the endometrium [81]

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Regulatory agencies like the FDA and EFSA have approved its use, and extensive studies confirm it is safe when used at recommended levels (typically 0.1% to 0.4% of flour weight)

10.1073/pnas.1321109111 91 Hayashi-TakagiA.TakakiM.GrazianeN.SeshadriS.MurdochH.DunlopA

Fatigue involves multiple neuroendocrine axes, and its abnormalities may originate from central nervous system dysfunction, which affects peripheral organs

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