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The results suggested that current approach is highly effective in the analysis of both soft and hard reactive metabolites and can be used as a high-throughput method in drug discovery.
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Ferroptosis is an iron-dependent form of necrotic cell death marked by oxidative damage to phospholipids....
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Mdivi-1 treatment also effectively inhibited mitochondrial fission regulatory protein markers, Drp1(Ser616) phosphorylation, and mitochondrial fission protein 1 (Fis1) in skeletal muscles from D2-mdx mice, which resulted in reduced content of damaged and fragmented mitochondria
