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Description
CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer

Their primary hormonal action is on the somatotropic axis: more GH, more IGF-1, more protein synthesis, and more favorable partitioning between fat and lean mass
Disclosure of interest: DL has received advisory board honoraria from Boehringer Ingelheim and a consultancy payment for this study from Bayer

This helps detect disposable addresses and adopt a sunset policy for inactive contacts, moving them into a separate segment or dropping them from future campaigns altogether
ABAD directly links Abeta to mitochondrial toxicity in Alzheimers disease
The cyanocobalamin form is an FDA-approved commercial product
