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CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer

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Their primary hormonal action is on the somatotropic axis: more GH, more IGF-1, more protein synthesis, and more favorable partitioning between fat and lean mass

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Disclosure of interest: DL has received advisory board honoraria from Boehringer Ingelheim and a consultancy payment for this study from Bayer

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