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4 Copper and mitochondria 4.1 Copper metabolism and mitochondria The body obtains copper from the diet, which is absorbed by the epithelial cells of the small intestine and transported through the portal vein to the liver, where it enters the bloodstream or is excreted through the bile (Maung et al., 2021)

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PD is caused by the disruption of dopaminergic neurotransmission in the basal ganglia, which causes a reduction in the numbers of dopaminergic neurons in the substantia nigra and formation of cytoplasmic inclusions called Lewy bodies [1]

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