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Countless studies have found that glutathione levels are significantly depleted in ageing populations and those with mental health conditions
Overall, these results indicate that the regulation of ferroptosis sensitivity by IRE1 can be modulated pharmacologically

doi: 10.1007/s10787-999-0023-y

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Isoniazid (INH) and rifampicin (RFP) used in combination are the first-line anti-TB regimen and metabolized in the liver accompanied by liver toxicity with large consumption of intracellular GSH, leading lipid peroxidation and hepatocyte death [152]
