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These fibrils bundle together to create fibers, and fibers aggregate to form the ligament
Interestingly, despite the deactivating ester functional group adjacent to the carbon nucleophile, this study reports that the -ketoester probe has enhanced reactivity, as compared to dimedone

evaluated the effect of zerumbone-loaded LCNs (ZER-LCNs) in cigarette smoke extract (CSE)-induced models [174]

Subsequently, other authors confirmed the life-extending ability of D

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For example, DAMPs such as HMGB1, S100A8/A9, cfDNA, and oxidized low-density lipoprotein (oxLDL) can interact with TLRs, leading to the activation of NF-B and IRF3 pathways through MyD88-dependent or -independent mechanisms
