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Therefore, we speculate that the decrease in NCOA4 levels after cerebral ischemia mediates a decrease in ferritinophagy, leading to ferritin accumulation

10.1183/23120541.00495-2022 ERJ Open Res

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Mechanistically, eATP (a prototypic DAMP) engages purinergic receptors, notably P2X 7 R (but also P2Y 11 in neutrophils), to initiate signalling programs intersecting with lipid metabolic enzymes needed for vesicle biogenesis [20]
