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Estrogen signaling and disruption of androgen metabolism in acquired androgenindependence during cadmium carcinogenesis in human prostate epithelial cells

Cellular 4-HNE levels are regulated through metabolism including its Phase II conjugation with GSH

Interestingly, zinc imbalance has been linked to the hypermethylation and silencing of zinc transporters such as ZIP8 and ZIP13, suggesting a feedback loop between zinc status, transporter expression and nuclear epigenetic regulation 116,117

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These features are aggravated by an inflexible adherence to routines and inadequate reaction to sensory stimulation

[DOI] [PubMed] [Google Scholar] 40.Nikolaidis MG, Paschalis V, Giakas G