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Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth

8% with placebo), and 62 and 49% at week 52 on UPA 30 and 15 mg, respectively
It was given the name H
Comparison with human mitochondrial thioredoxin Reduced form of human mitochondrial thioredoxin (PDB code 1UVZ) was superimposed on PfTrx-2 using Chimera 29

2017;15 doi: 10.2903/j.efsa.2017.5060

[PubMed 11449879] 2357
