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COX-2 not only interacts with neurotransmitters such as ACH, 5-HT, and Glu but also participates in the immune and inflammatory responses of the CNS through prostaglandin E 2 (PGE2) [136]

Biochemical analysis The current study demonstrated that exposing rats to 10 Gy head irradiation induced oxidative stress, mitochondrial dysfunction, inflammation, and cellular senescence in brain tissue

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Both compounds reduced dopamine neuron firing, but through distinct receptor mechanisms

Systemic subcutaneous administration of four classic convulsant agentspentylenetetrazol (PTZ), pilocarpine, lycorine, and kainic acidconsistently elevated KYNA levels in vivo [31]

Strategic Moves: A new Corporate Performance & ESG division was formed, and investment in product development rose to 11% of revenues