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Loss of autophagy in the central nervous system causes neurodegeneration in mice

G2 plants showed a 0.98 fold rise in fresh weight as compared to control

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Also, the levels of GSH, in both livers and testes tissues of male rabbits, were significantly decreased after treatment with Sildenafil, Tadalafil, and Vardenafil (Table 3)

The activation of clockophagy selectively degrades ARNTL through cargo receptor sequestosome 1 (SQSTM1), destabilizing HIF1A protein, and ultimately exacerbating lipid peroxidation and ferroptosis[71]