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The overall safety profile appears favorable, with serious adverse events being relatively rare and consistent with the broader GLP-1 receptor agonist class

The most common side effects of Zepbound are: nausea, diarrhea, vomiting, constipation, stomach pain, indigestion, injection site reactions, feeling tired, allergic reactions, belching/gas, hair loss, and heartburn

In most cases, vitamins are unable to be produced or synthesised by the body and if the body's level of vitamins are reduced the risk of developing vitamin specific deficiencies are increased