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Crit Rev Eukaryot Gene Expr (1993) 3(3):15566

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Lipotoxicity modeled through chronic exposure to 0.5 mM palmitate increases superoxide/mtROS production, and decreases enzymes related to carbon metabolism such as citrate synthase (Maris et al., 2013)

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Modulating the signaling pathways that cause the inflammatory response and improve the immune function of patients has become the focus of reducing inflammatory damage in the lungs, especially CAP in older adults

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The differential metabolites and metabolic pathways identified in this paper should be further studied using targeted metabolomics, lipidomics, and proteomics, in order to elucidate mechanisms and screening therapeutic targets for developing early diagnostic strategies and treatments

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