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Science 287 , 14971500 (2000)

*Correspondence: C (Linda) MC van Campen, [email protected] This article was submitted to Pharmaceutical Medicine and Outcomes Research, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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In terms of patients diagnosed with idiopathic generalized epilepsy or unclassifiable seizures, VPA remains also the candidate while lamotrigine and topiramate should not be considered in these patients due to lower efficacy and intolerable profiles [158]