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Some of this initial loss is water weight from reduced glycogen stores

In a seminal study in diet-induced obese mice, 5-amino-1MQ administration led to a 35% reduction in mass and size, a 30% decrease in adipocyte size, and a 40% decrease in adipocyte volume in the rodents

Elevated insulin inhibits hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides

& Zechner, R
