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Acetylcarnitine can up-regulate the expression of voltage-dependent anion channel gene in rat brain, which plays an important role in synaptic plasticity [110]

J Hazard Mater

SCFA regulate cytokines such as TNF-, interleukin 6 (IL-6), and IL-10, which affect inflammation and immune cell activity

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Although osteoarthritis is the leading cause of disability and the 15th highest cause of years lived with disability worldwide, no cure or disease-modifying treatments are available [2, 6]

Mitochondrial trifunctional protein (MTP) defects are disorders of mitochondrial fatty acid -oxidation pathway of which progressive pigment chorioretinopathy is a long-term complication [164]
