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Systemically reducing expression of the long PRLR isoform using a novel method reduced metastases in the aggressive 4T1 model, and PRL-supported immunosuppressive Tregs were identified as a major target (83, 130)
K., Dolman D

The gut microbiome constitutes a critical, non-host component of the systemic amino acid metabolic network

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doi: 10.3390/ijms21186710

Besides, transcription factors like Nrf2 and p53 act as crucial ROS-related biomarkers in cancer diagnosis and treatment, balancing between protecting cells from oxidative stress and contributing to tumor growth under certain conditions
