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Bupropion, a nonselective dopamine- and norepinephrine-reuptake inhibitor, is considered to reduce weight by stimulating hypothalamic POMC neurons

Older adults are more likely to be deficient in vitamin B12 due to a number of factors, including decreased stomach acid production and decreased absorption of vitamin B12 from food

Its principal relevance is in the prevention and/or cure of black tongue and pellagra