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Zhang W, Ye Y, Song J, Sang T, Xia T, Xie L, et al

In conclusion, we have identified a novel NADPH- and glutathione-dependent pathway through which TCA cycle activity impacts ER homeostasis

& Kiyama, H

Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury

Psychiatry 34 LeeM.ChoT.JantaratnotaiN.WangY

Introduction Glutathione S -transferases (GSTs) are a family of enzymes that conjugate reduced glutathione (GSH) to target molecules in the phase II detoxification of xenobiotic metabolism ( Here we examined the mechanisms of how GSTM1 regulates astrocyte transcriptional program in response to pro-inflammatory signaling and further addressed the impact of GSTM1 loss-of-function on neurons during acute brain inflammation following a systemic injection of lipopolysaccharides (LPS)
