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In addition, TIM3 inhibition may prime the recruitment of cytotoxic T cells or reinvigoration of exhausted T cells to the tumor site under the metastatic setting
A careful risk/benefit evaluation must therefore be performed when planning the enrollment of children, especially before widespread clinical application [314]

[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Schwab U., Torronen A., Toppinen L., Alfthan G., Saarinen M., Aro A., Uusitupa M
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10.1016/0162-0134(92)84013-d [DOI] [PubMed] [Google Scholar] Apostolopoulos V., Bojarska J., Chai T

Proteostasis and aging

Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach
