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Description
22 Mutation of specific phosphorylation sites may be used as a strategy for treating fibrosis and even liver cirrhosis caused by HSC activation

M.BecanaM

Pharmacology research & perspectives
When intake is frequent, doses accumulate, or detox capacity is impaired, glutathione becomes depletedallowing NAPQI to build up and trigger liver cell injury and death (17)

Following the encouraging results as single agent, daratumumab was evaluated in combination with immune checkpoint inhibitors, immunomodulatory drugs and proteasome inhibitors (Fig

10.3389/fphar.2019.00466 153 ThieleckeF.RahnG.BohnkeJ.AdamsF.Birken feldA
