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Novel mechanisms and therapeutic targets in atherosclerosis: inflammation and beyond

Chest 117 , 10S14S (2000)

The classic Russell mechanism involves the combination of two peroxyl radicals followed by the elimination of singlet oxygen and formation of one alcohol and one ketone

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Genetic variations in the expression of drug transporters in the gut wall (e.g., P-glycoprotein) can cause significant inter-individual differences in drug absorption