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Once a store of vitamin B12 is built up, this can supply the bodys needs for several months

doi: 10.1007/s00438-018-1517-3 Pubmed Abstract CrossRef Google Scholar View reference in article 34 MrowickaMagorzataMrowickiJDraganGMajsterekI

Zhou, Glycyl-L-histidyl-L-lysine-Cu2+ attenuates cigarette smoke-induced pulmonary emphysema and inflammation by reducing oxidative stress pathway, Frontiers Media SA, Jul
10.1614/WS-05-54.2.230 7 AsadaK

The comparison to vitamin C and retinoic acid (70% vs 50% vs 40% collagen improvement) is cited widely but comes from a single study
