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Detailed information about the sample preparation, detection, and quantification of metabolites can be found in the Supplemental Data Sheet

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Due to its anti-inflammatory effects, researchers are beginning to investigate it as a possible therapeutic option for the novel coronavirus (SARS-CoV-2), which causes the disease COVID-19 ( Still, rigorous research on the effectiveness of pine bark extract in humans is lacking, and more randomized controlled-trial studies are needed

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La microbiota intestinal sufre cambios en su composicin, incrementando las familias con capacidad para sintetizar urea, cido rico y otros compuestos como los indoles y fenoles, los cuales traspasan la barrera intestinal debido a la disfuncionalidad de la misma 1