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While Hsp90 and TSLP inhibitors have not yet been applied in BP, a phase II open label trial in BP with AC-203, a topical agent interfering with inflammasome and IL-1 pathways, was terminated prematurely (NCT03286582) [124]

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Gupta A, Mathur R, Singh S, Bag N, Khan UA, Ahmad FJ, Gabr GA, Kesharwani P, Jain GK