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Organs-on-a-chip: A new tool for drug discovery

doi: 10.1007/s00394-019-01901-0 161 FanXLiuYHeZBaiY

This study aimed to investigate the potential hepatoprotective effects of L-carnitine (LCR), a mitochondrial cofactor with antioxidant and anti-apoptotic properties, in a rat model of MTX-induced hepatotoxicity

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Moreover, small clinical trials in prediabetes and obesity (48 g day 1 ) improved postprandial glucose, increased mucosal-associated invariant T (MAIT) cells, as well as shifted the gut microbiota and the epigenetic regulation of the amino acid transporter SLC7A5 (refs