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After aggregate formation, differentiation was initiated to drive pluripotent hPSC aggregates to primitive streak/mesendoderm (Day 1) and further patterned toward definitive endoderm (Day 2) (see Fig

doi: 10.1007/s10654-018-0450-4 5

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Examples of these factors include exposure to cold temperatures, ionizing radiation, high sugar levels, cigarette smoking, and environmental pollution

Since vitamin B12 contains the mineral cobalt, it's sometimes known as cobalamin

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