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The HCV-specific CD8 + T cells expressing PD-1, a marker for exhaustion, were found at the time of the acute phase[236]

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Disrupting the p53/MDM2 interaction using molecules like ISA27 and nutlin-3a, or employing p53-binding circular RNAs (e.g., CDR1as), can effectively reinstate p53 activity and trigger apoptosis in undifferentiated GBM cells, thereby impeding tumor progression (Esemen et al., 2022)

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Ninety-three percent of the kids displaying symptoms tested positive for COVID-19 or its antibodies