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Micronutrient Deficiencies in Morbidly Obese Women Prior to Bariatric Surgery

Well-documented cases exist, but the term is often applied to whatever a nonspecific precipitation step removes, and some studies use methods that cannot actually confirm what was present

For example, dosages of 1,000 mcg or more are routinely used to treat deficiencies without major concern for toxicity

Possible explanations include unacceptable toxicity in human subjects, business strategy changes at Arrowhead Research Corporation (which shifted focus to RNA therapeutics), regulatory challenges, or a combination of factors
