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[DOI] [PubMed] [Google Scholar] 61.Itoh M, et al

Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs

Common dosing scenarios and their J3010 unit calculations include procedural sedation at 50100 mcg billed as 1 unit, anaesthesia induction at 100200 mcg billed as 12 units, and breakthrough pain management at 2550 mcg billed as 1 unit (rounded up from a sub-unit dose)

Your provider will adjust the dose based on your condition, body weight, treatment goals, and overall medical assessment

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