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5 Mitochondrial ROS imbalance in the molecular pathogenesis of supraspinatus muscle atrophy 5.1 Oxidative stress-induced damage triggered by ROS imbalance 5.1.1 Oxidative modification of proteins, lipids, and DNA Reactive oxygen species (ROS) induce oxidative damage to skeletal muscle macromolecules, disrupting structural integrity and biological function

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[DOI] [PMC free article] [PubMed] [Google Scholar] 188.Romero I.L., Mukherjee A., Kenny H.A., Litchfield L.M., Lengyel E

121 Together, these observations provide evidence for ferroptotic cell death in the livers of mice exposed to a single high-dose combination of rifampicin and isoniazid, as well as in patients treated with these drugs