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The Role of the Ectopeptidase APN/CD13 in Cancer

Alengebawy A, Abdelkhalek ST, Qureshi SR, Wang M-Q

The fetal brain, especially in the early stages of development, has limited inflammatory potential, but viral-induced destruction of neural tissue in the early fetus may be accompanied by an intense macrophage reaction despite lack of immunologic maturity

It is designed for laboratory studies focused on peptide behavior and interactions in non-clinical models

In conclusion, the evolving landscape of glutamine deprivation strategies in cancer therapy highlights the diverse approaches to disrupting glutamine metabolism in specific vital cellular nodes

These findings suggest that NaB may serve as an effective adjuvant therapy in ovarian cancer, potentially allowing for lower doses of paclitaxel and reducing the associated side effects
