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10.1186/s13054-014-0460-x 148 OzkokE.YorulmazH.AtesG.AksuA.BalkisN.ahin.et al (2016)

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Prior studies have shown that neurometabolite concentrations tend to show more drastic changes when assessed during active stimulus application compared to the resting state in chronic pain conditions ( Regarding the second hypothesis, the findings suggest that alterations in insula neurometabolites in Crohns disease patients may be associated with the manifestation of symptoms and pain catastrophizing

Results The mean ( SD) baseline predicted forced expiratory volume in 1 s (FEV 1 ) of the 30 subjects who completed the study was 51 15%, with a FEV 1 /forced vital capacity ratio of 50 11%