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The administration of acetyl-l-carnitine along with MA (increasing from 1 to 5 mg/kg, i.p.) for 10 days was shown to attenuate the severity of symptoms caused by non-use of the drug during the subsequent 10-day withdrawal period in Wistar rats 45

However, a 2014 study in the Journal of Physiology suggested that L-carnitine L-tartrate might be particularly effective in enhancing mitochondrial FunctionFunction in muscle tissue (Wall et al., 2014)

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however, further long-term intervention studies with a larger sample size may be needed to clarify lipid-lowering effects after L-carnitine intervention in patients with hyperlipidemia